Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 5/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419928 | 0.82 | NPC1 (0.41) | ALDH1A1PARP10PARP11PIM1PIM2 | |
| SCHEMBL26512083 | 0.77 | TDP2 (0.38) | ALDH1A1PARP10PARP11MEN1KMT2A | |
| SCHEMBL2427753 | 0.74 | RAB9A (0.37) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL2425515 | 0.70 | MAPT (0.43) | MAPKAPK2CDK1MEN1KMT2APDE4B | |
| SCHEMBL5230177 | 0.64 | PARP1 (0.46) | ALDH1A1PIM1CSNK2A1DYRK1ACLK4 | |
| SCHEMBL794250 | 0.63 | PARP11 (0.44) | PARP10PARP11PIM1CSNK2A1DYRK1A | |
| SCHEMBL26512104 | 0.63 | MAPKAPK2 (0.35) | MAPKAPK2MKNK1MKNK2 | |
| SCHEMBL5320061 | 0.62 | CYP1A2 (0.31) | — | |
| SCHEMBL5393255 | 0.62 | POLB (0.46) | ALDH1A1PIM1CSNK2A1DYRK1ACLK4 | |
| SCHEMBL3794487 | 0.62 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1540329-A4 | DRUG DISCOVERY METHOD | KEDDEM BIO SCIENCE LTD (IL) | 2009-06-10 | — | — | EP | disclosed |
| EP-1540329-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004010136-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2004-01-29 | — | — | WO | disclosed |