Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328322 | 0.88 | ESR1 (0.48) | ESR1ESR2CA2CAMK2AKDM4E | |
| SCHEMBL4333356 | 0.83 | KMT2A (0.55) | OPRM1OPRD1OPRK1ALDH1A1CYP2C19 | |
| SCHEMBL11331545 | 0.82 | KDM4E (0.52) | ESR1ESR2CA2CAMK2AOPRM1 | |
| SCHEMBL8758089 | 0.80 | ESRRG (0.56) | ESR1ESR2CA2CAMK2AOPRM1 | |
| SCHEMBL1578297 | 0.77 | CYP1A2 (0.41) | ESR1ESR2OPRM1OPRD1OPRK1 | |
| SCHEMBL4147783 | 0.76 | ESRRG (0.49) | ESR1ESR2CA2CAMK2AOPRM1 | |
| SCHEMBL4753457 | 0.75 | ALOX5 (0.53) | ESR1ESR2CA2CAMK2AKDM4E | |
| SCHEMBL4328328 | 0.75 | CALM1 (0.46) | ESR1ESR2KDM4EALDH1A1ADRA2A | |
| SCHEMBL28600447 | 0.73 | ESR1 (0.50) | ESR1ESR2CA2OPRM1OPRD1 | |
| SCHEMBL25337380 | 0.73 | ESR1 (0.45) | ESR1ESR2CA2CAMK2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |