Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319911 | 0.86 | ATM (0.33) | KDM4EMAPTGLAALDH1A1GAA | |
| SCHEMBL4454609 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL4476207 | 0.70 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3LMNACYP2D6 | |
| SCHEMBL4463813 | 0.68 | KDM4E (0.39) | KDM4EMAPTGLAALDH1A1GAA | |
| SCHEMBL5275095 | 0.63 | KDM4E (0.56) | KDM4EMAPTGLAALDH1A1GAA | |
| SCHEMBL4469390 | 0.61 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9806370 | 0.60 | CYP2C19 (0.56) | KDM4EMAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL19130800 | 0.60 | CYP2C19 (0.56) | KDM4EMAPTALDH1A1CYP3A4CYP1A2 | |
| Oxalic Acid SCHEMBL22721071 | 0.59 | HCRTR1 (0.43) | KDM4EMAPTGLAALDH1A1GAA | |
| SCHEMBL22728572 | 0.59 | HSD17B10 (0.49) | KDM4EMAPTALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |