Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353212 | 0.82 | ALDH1A1 (0.41) | CA12CA1CA2CA7XDH | |
| SCHEMBL10247203 | 0.79 | NPC1 (0.46) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL26227721 | 0.75 | ALDH1A1 (0.39) | CA12CA1CA2CA7XDH | |
| SCHEMBL23112216 | 0.74 | SMN1; SMN2 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10215462 | 0.74 | SLC6A2 (0.56) | CA12CA1CA2CA7XDH | |
| SCHEMBL11152269 | 0.74 | SLC6A2 (0.56) | CA12CA1CA2CA7XDH | |
| SCHEMBL16961717 | 0.73 | SLC6A2 (0.33) | CA1CA2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16962887 | 0.73 | CHRNB2 (0.35) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18682115 | 0.72 | CA1 (0.55) | CA12CA1CA2CA7XDH | |
| SCHEMBL18670723 | 0.72 | CA1 (0.55) | CA12CA1CA2CA7XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |