Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333810 | 0.87 | PDE10A (0.52) | PDE10AAOC3 | |
| SCHEMBL4332133 | 0.85 | AOC3 (0.55) | PDE10AAOC3 | |
| SCHEMBL27809064 | 0.81 | AOC3 (0.43) | PDE10AAOC3 | |
| SCHEMBL4340373 | 0.77 | MAPT (0.45) | GAATSHR | |
| SCHEMBL4331617 | 0.76 | AGXT (0.55) | AOC3 | |
| SCHEMBL4328135 | 0.75 | AOC3 (0.51) | AOC3TSHR | |
| SCHEMBL27809009 | 0.73 | KCNH2 (0.37) | — | |
| SCHEMBL6475308 | 0.72 | GAA (0.51) | PDE10AGAACXCR4PIK3CAMTOR | |
| SCHEMBL1844501 | 0.72 | PDE10A (0.50) | PDE10AGAACXCR4TSHRPIK3CA | |
| SCHEMBL1303138 | 0.72 | PDE10A (0.50) | PDE10AGAACXCR4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |