Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.39 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.39 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340373 | 0.87 | MAPT (0.45) | AGXTLMNASIGMAR1TMEM97ADRA2A | |
| SCHEMBL4328642 | 0.87 | PRMT6 (0.54) | AGXTSIGMAR1PRMT6L3MBTL3L3MBTL1 | |
| SCHEMBL4337043 | 0.83 | HTR7 (0.50) | SIGMAR1HTR2B | |
| SCHEMBL3141768 | 0.81 | AGXT (0.48) | AGXTLMNAKMO | |
| SCHEMBL27809061 | 0.81 | NCF1 (0.58) | SIGMAR1PRMT6 | |
| SCHEMBL159425 | 0.78 | LMNA (0.59) | AGXTLMNAKMO | |
| SCHEMBL27425605 | 0.78 | MAPT (0.44) | AGXTLMNASIGMAR1TMEM97ADRA2A | |
| SCHEMBL27829456 | 0.78 | RORC (0.46) | AOC3 | |
| SCHEMBL13725027 | 0.78 | AGXT (0.66) | AGXTLMNAKMOAOC3SIGMAR1 | |
| SCHEMBL8189516 | 0.78 | AGXT (0.61) | AGXTLMNAKMOAOC3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |