Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714287 | 0.83 | TSHR (0.68) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL16902654 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL16905806 | 0.80 | KDM4E (0.65) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL2392417 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL15714138 | 0.80 | TSHR (0.73) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL17179775 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL4346565 | 0.78 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL17179761 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL15714263 | 0.75 | KDM4E (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL4338164 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |