Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826516 | 0.79 | GRM5 (0.62) | GRM5ADAMTS5TSHRHTTMAPK1 | |
| SCHEMBL2032174 | 0.79 | GRM5 (0.62) | GRM5ADAMTS5TSHRHTTMAPK1 | |
| SCHEMBL13673750 | 0.78 | KMT2A (0.52) | GRM5ADAMTS5MAPK1ALDH1A1MEN1 | |
| SCHEMBL4334098 | 0.77 | GRM5 (0.54) | GRM5ADAMTS5TSHRHTTMMP2 | |
| SCHEMBL4467696 | 0.77 | GRM5 (0.62) | GRM5ADAMTS5TSHRHTTMAPK1 | |
| SCHEMBL15084146 | 0.77 | GRM5 (0.58) | GRM5ADAMTS5TSHRHTTMAPK1 | |
| SCHEMBL4334106 | 0.75 | GRM5 (0.54) | GRM5ADAMTS5TSHRMAPK1POLB | |
| SCHEMBL15081817 | 0.74 | GRM5 (0.55) | GRM5ADAMTS5TSHRHTTMAPK1 | |
| SCHEMBL17884480 | 0.74 | ADAMTS5 (0.66) | GRM5ADAMTS5TSHRHTTMMP2 | |
| SCHEMBL16472154 | 0.73 | SLC1A1 (0.53) | TSHRMAPK1SLC1A1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021015-A2 | GHRELIN/GROWTH HORMONE RELEASING PEPTIDE/GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | The Administrators Of The Tulane Educational Fund (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007127457-A9 | GHRELIN/GROWTH HORMONE RELEASING PEPTIDE/GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | UNIV TULANE (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2007127457-A2 | GHRELIN/GROWTH HORMONE RELEASING PEPTIDE/GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-11-08 | — | — | WO | disclosed |