Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | ME2 | P23368 | 2/20 | 0.47 |
| ▸ | ME1 | P48163 | 2/20 | 0.47 |
| ▸ | ME3 | Q16798 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032174 | 0.85 | GRM5 (0.62) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL826516 | 0.85 | GRM5 (0.62) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL15084146 | 0.81 | GRM5 (0.58) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL15081817 | 0.79 | GRM5 (0.55) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL4334098 | 0.78 | GRM5 (0.54) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL4334106 | 0.78 | GRM5 (0.54) | GRM5TSHRMAPK1ADAMTS5POLB | |
| SCHEMBL4334109 | 0.77 | GRM5 (0.53) | GRM5TSHRHTTMAPK1ADAMTS5 | |
| SCHEMBL1902638 | 0.77 | GRM5 (1.00) | GRM5ME2ME1ME3LMNA | |
| SCHEMBL27736436 | 0.76 | TSHR (0.62) | GRM5TSHRHTTMAPK1ME2 | |
| SCHEMBL2021273 | 0.76 | GHSR (0.60) | GRM5TSHRMAPK1POLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021015-A2 | GHRELIN/GROWTH HORMONE RELEASING PEPTIDE/GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | The Administrators Of The Tulane Educational Fund (US) | 2009-02-11 | — | — | EP | claimed |
| WO-2007127457-A2 | GHRELIN/GROWTH HORMONE RELEASING PEPTIDE/GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-11-08 | — | — | WO | claimed |