SCHEMBL4334133

SCHEMBL4334133

CN1C(C)(C)CCC(C(CC(=O)O)(C(=O)O)C2CCC(C)(C)N(C)C2(C)C)C1(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5889385 0.71 TSHR (0.33) TSHRNFKB1CYP2C19
SCHEMBL7568939 0.66 SLC1A2 (0.42) TSHRNFKB1CYP2C19
SCHEMBL4573970 0.66
SCHEMBL317177 0.65 GAA (0.33) TSHRCYP2C19
Citric Acid SCHEMBL986674 0.65 ALDH1A1 (0.52) TSHRNFKB1CYP2C19
Citric Acid SCHEMBL986672 0.65 ALDH1A1 (0.52) TSHRNFKB1CYP2C19
SCHEMBL11200071 0.64
SCHEMBL8396988 0.61 CHRM3 (0.42) TSHRNFKB1
SCHEMBL8396984 0.61 CHRM3 (0.42) TSHRNFKB1
SCHEMBL11200066 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054565-A1 Flame-Retardant plastics molding composition CLARIANT INTERNATIONAL LTD. 2009-02-26 US disclosed
EP-2028227-A1 Flame-resistant plastic moulding material CLARIANT INTERNATIONAL LTD. (CH) 2009-02-25 EP disclosed
EP-0576833-B1 Process for preparing hydrolytically stable trivalent phosphorus compounds and their use as stabilisers for thermoplastic materials CLARIANT GMBH (DE) 2001-03-07 EP disclosed
EP-0517128-B1 Use of a carboxylic acid anhydride to manufacture a polyolefin moulding composition ELENAC GMBH (DE) 2000-01-26 EP disclosed
US-6013706-A Process for the preparation of hyrolysis-stable trivalent phosphorus compounds and their use as stabilizers for thermoplastics CLARIANT GMBH (DE) 2000-01-11 US disclosed
EP-0668283-B1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds CLARIANT GMBH (DE) 1998-05-20 EP disclosed
EP-0584567-B1 Fire retardant polymer compositions with increased stability CLARIANT GMBH (DE) 1998-01-28 EP disclosed
EP-0485891-B1 Process for the reduction of discoloration of a polymeric moulding composition at processing temperature HOECHST AG (DE) 1997-05-02 EP disclosed
EP-0402889-B1 Polymeric polyalkyl-1-oxadiazaspirodecanes HOECHST AG (DE) 1996-09-04 EP disclosed
EP-0668283-A1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
EP-0668282-A1 Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
US-5326805-A Flame-retardant plastics molding composition of improved stability HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
EP-0599284-A1 Cyclo-olefin polymer moulding composition with improved stability against chemical degradation HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-01 EP disclosed
EP-0584567-A2 Fire retardant polymer compositions with increased stability HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-02 EP disclosed
EP-0576833-A2 Process for preparing hydrolytically stable trivalent phosphorus compounds and their use as stabilisators for thermoplastic materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed
EP-0517128-A2 Use of a carboxylic acid anhydride to manufacture a polyolefin moulding composition HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-09 EP disclosed
EP-0489050-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-10 EP disclosed
EP-0485891-A2 Process for the reduction of discoloration of a polymeric moulding composition at processing temperature HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-20 EP disclosed
WO-1991002738-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO disclosed
EP-0402889-A2 Polymeric polyalkyl-1-oxadiazaspirodecanes HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-19 EP disclosed