Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24130627 | 0.79 | HPGD (0.54) | HPGDHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL8099116 | 0.79 | HPGD (0.61) | HPGDHDAC2HDAC8HDAC6MAPT | |
| SCHEMBL24130629 | 0.79 | HPGD (0.54) | HPGDHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL1661081 | 0.78 | TRPV1 (0.76) | HPGDHDAC2HDAC8HDAC6ALOX15 | |
| SCHEMBL2186352 | 0.78 | HDAC2 (0.72) | HPGDHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL7455811 | 0.78 | HDAC2 (0.66) | HPGDHDAC2HDAC8HDAC6ALOX15 | |
| SCHEMBL23180466 | 0.78 | HPGD (0.73) | HPGDHDAC2HDAC8HDAC6HDAC1 | |
| Hydrocinnamoylglycine SCHEMBL3995983 | 0.77 | HDAC2 (0.63) | HPGDHDAC2HDAC8HDAC6ALOX15 | |
| SCHEMBL5196581 | 0.77 | HDAC2 (0.63) | HPGDHDAC2HDAC8HDAC6ALOX15 | |
| SCHEMBL7450998 | 0.77 | HDAC2 (0.63) | HPGDHDAC2HDAC8HDAC6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |