Sugi Predict

Sugi Predict / Compounds / SCHEMBL2186352

SCHEMBL2186352

SCHEMBL2186352

O=C(CCc1ccccc1)NCCc1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC2 Q92769 3/20 0.72
▸ HDAC8 Q9BY41 3/20 0.72
▸ HDAC6 Q9UBN7 3/20 0.72
▸ HDAC3 O15379 2/20 0.72
▸ HDAC1 Q13547 2/20 0.72
▸ HDAC10 Q969S8 2/20 0.72
▸ HDAC11 Q96DB2 2/20 0.72
▸ NCOR2 Q9Y618 2/20 0.72
▸ HDAC4 P56524 1/20 0.72
▸ HDAC9 Q9UKV0 1/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.70
▸ HPGD P15428 2/20 0.70
▸ PLAAT5 Q96KN8 1/20 0.68
▸ PLAAT4 Q9UL19 1/20 0.68
▸ MEN1 O00255 1/20 0.68
▸ RAB9A P51151 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ KDM4E B2RXH2 1/20 0.66
▸ LMNA P02545 1/20 0.66
▸ TAAR1 Q96RJ0 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765076 0.94 L3MBTL1 (0.79) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL4151866 0.91 GAA (0.74) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL4151976 0.91 GAA (0.74) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL4074353 0.90 HDAC3 (0.87) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL15679869 0.90 PLAAT3 (0.73) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL166980 0.89 L3MBTL1 (0.71) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL3681101 0.89 CNR2 (0.68) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL6290165 0.89 HPGD (0.66) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL8744900 0.89 HPGD (0.81) HDAC2HDAC8HDAC6HDAC3HDAC1
SCHEMBL13073412 0.89 HDAC3 (0.78) HDAC2HDAC8HDAC6HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170029644-A1 PHASE CHANGE INKS COMPRISING CRYSTALLINE AMIDES XEROX CORPORATION 2017-02-02 — — US claimed
EP-2661436-B1 NOVEL SULFAMIDE PIPERAZINE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF LEO PHARMA AS (DK) 2016-04-13 — — EP claimed
US-20130284060-A1 PHASE CHANGE INKS COMPRISING CRYSTALLINE AMIDES XEROX CORPORATION (US) 2013-10-31 — — US claimed
US-8328924-B2 Phase change inks and methods of making the same XEROX CORPORATION (US) 2012-12-11 — — US claimed
US-20120272864-A1 PHASE CHANGE INKS AND METHODS OF MAKING THE SAME XEROX CORPORATION (US) 2012-11-01 — — US claimed
EP-2342180-A2 ORGANIC COMPOUNDS SUITABLE FOR MODULATING FRAGRANCE COMPOSITIONS Givaudan SA (CH) 2011-07-13 — — EP claimed
WO-2010037244-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-04-08 — — WO claimed
US-20090111874-A1 Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) 2009-04-30 — — US claimed
EP-1876169-A1 PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2008-01-09 — — EP claimed
CN-101095648-A Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds OREAL (FR) 2008-01-02 — — CN claimed
CN-116121782-B Method for synthesizing tellurium-containing oxazolidinone compound by electrochemically fixing carbon dioxide and application thereof 桂林电子科技大学 2025-04-22 — — CN disclosed
CN-117919319-A Fructus Lycii water extract for improving female fertility and preparation method thereof 澳门科技大学 2024-04-26 — — CN disclosed
CN-116283648-B Substituted benzene acryloyl or benzene propionyl phenethylamine compound and preparation method and application thereof 中国医学科学院药用植物研究所 2024-03-19 — — CN disclosed
WO-2023171671-A1 METHOD FOR PRODUCING CYCLIC AMIDE 国立大学法人東海国立大学機構 2023-09-14 — — WO disclosed
WO-2023171671-A1 METHOD FOR PRODUCING CYCLIC AMIDE 国立大学法人東海国立大学機構 2023-09-14 — — WO disclosed
US-6852856-B2 Method for preserving quaternary ammonium salt TOKUYAMA CORPORATION (JP) 2005-02-08 — — US disclosed
EP-1085000-B1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND CONDENSING AGENT COMPRISING QUATERNARY AMMONIUM SALT TOKUYAMA CORP (JP) 2004-10-06 — — EP disclosed
US-20040147740-A1 Method for storing quaternary ammonium salt HIRANO NAOKI (JP) 2004-07-29 — — US disclosed
US-20030153785-A1 Method for preserving quaternary ammonium salt TOKUYAMA CORPORATION (JP) 2003-08-14 — — US disclosed
EP-1178043-A1 METHOD FOR STORING QUATERNARY AMMONIUM SALT TOKUYAMA CORPORATION (JP) 2002-02-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153785-A1 Method for preserving quaternary ammonium salt NHERF1, ASH1L, ATP6V1B1 HDAC2 155/4885HDAC8 185/4885HDAC6 7/4885
US-20090111874-A1 Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof PAH, MAOA, APEH HDAC2 1589/4885HDAC8 1766/4885HDAC6 1014/4885
US-20040147740-A1 Method for storing quaternary ammonium salt ASNS, ATP1B2, SCN7A HDAC2 271/4885HDAC8 362/4885HDAC6 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.