Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12557215 | 1.00 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL27858675 | 1.00 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL47340 | 1.00 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL29809913 | 1.00 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL27858674 | 1.00 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL4060357 | 0.98 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL3274216 | 0.89 | OPRM1 (0.57) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| Methylethylamine SCHEMBL5320200 | 0.88 | HIF1A (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| Propylamine SCHEMBL5320197 | 0.88 | OPRM1 (0.50) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL13310383 | 0.85 | OPRM1 (0.54) | ADRB1ADRA1AMIFHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026860-A | Preparation method of 3- [1- (dimethylamino) ethyl ] phenol | 福建福瑞明德药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-113461554-A | Purification method of rivastigmine intermediate | 北京泰德制药股份有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-109507344-A | Rivastigmine intermediate and its method for separating and detecting in relation to substance | 万特制药(海南)有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106565543-B | A kind of preparation method of rivastigmine-hydrogentartrate | 昆明源瑞制药有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-107334740-A | For stable rivastigmine-hydrogentartrate piece of fortified phenol and preparation method thereof | 万全万特制药江苏有限公司 | 2017-11-10 | — | — | CN | claimed |
| CN-104987294-B | A kind of preparation method of 3 [1 (dimethylamino) ethyl] phenol | 浙江京新药业股份有限公司 | 2017-08-15 | — | — | CN | claimed |
| CN-106565543-A | Preparation method of rivastigmine tartrate | 昆明源瑞制药有限公司 | 2017-04-19 | — | — | CN | claimed |
| EP-1856036-B1 | AN EFFICIENT METHOD FOR PREPARATION OF (S)-3-[(1-DIMETHYL AMINO)ETHYL]-PHENYL-N-ETHYL-N-METHYL-CARBAMATE | EMCURE PHARMACEUTICALS LTD (IN) | 2016-12-14 | — | — | EP | claimed |
| CN-104151176-B | A kind of Rivastigmine chiral intermediate and preparation method thereof | 大连韦德生化科技有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-103193600-B | The preparation method of rivastigmine intermediate | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-101580482-A | Method for preparing rivastigmine hydrogen tartrate and application thereof | UNIV SHENYANG PHARMACEUTICAL (CN) | 2009-11-18 | — | — | CN | claimed |
| CN-100457722-C | Method for synthesis of rivastigmine | UNIV JINAN (CN) | 2009-02-04 | — | — | CN | claimed |
| EP-1991524-A1 | A PROCESS FOR THE PREPARATION OF PHENYLCARBAMATES | Apotex Pharmachem Inc. (CA) | 2008-11-19 | — | — | EP | claimed |
| CN-101270058-A | Process for preparing 3-(1-dimethylamino- ethyl)phynol | BEIJING DEZHONG WANQUAN MEDICINE TECHNOLOGY DEV CO LTD (CN) | 2008-09-24 | — | — | CN | claimed |
| US-7385076-B2 | Process for the preparation of phenylcarbamates | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2008-06-10 | — | — | US | claimed |
| WO-2007098573-A1 | A PROCESS FOR THE PREPARATION OF PHENYLCARBAMATES | APOTEX PHARMACHEM INC. (CA) | 2007-09-07 | — | — | WO | claimed |
| US-20070207990-A1 | Process for the preparation of phenylcarbamates | APOTEX PHARMACHEM INC. (CA) | 2007-09-06 | — | — | US | claimed |
| CN-1962624-A | Method for synthesis of rivastigmine | UNIV JINAN (CN) | 2007-05-16 | — | — | CN | claimed |
| US-20060293518-A1 | Proccess for the preparation of phenylcarbamates | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2006-12-28 | — | — | US | claimed |
| CN-1486973-A | Ethyl methyl 3-[(1s)-1-(dimethylamino) ethyl] phenyl carbamate and its prepn and medicine use | 上海三维制药有限公司 | 2004-04-07 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293518-A1 | Proccess for the preparation of phenylcarbamates | CBR3, CBR1, C9 | ADRB1 693/4885ADRA1A 1104/4885MIF 4780/4885 |
| US-20070207990-A1 | Process for the preparation of phenylcarbamates | CYP2B6, CBR3, CBR1 | ADRB1 392/4885ADRA1A 1026/4885MIF 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.