Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | INPP5B | P32019 | 1/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759513 | 0.85 | MAPT (0.67) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL497309 | 0.85 | MAPT (0.67) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL29429257 | 0.85 | MAPT (0.67) | MAPTPOLBINPPL1INPP5BINPP5A | |
| Phosphoric Acid SCHEMBL27473336 | 0.83 | MAPT (0.65) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL4119537 | 0.83 | MAPT (0.65) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL19348791 | 0.81 | MAPT (0.73) | MAPTPOLBLMNAGAAMAPK1 | |
| SCHEMBL28473317 | 0.81 | MAPT (0.62) | MAPTPOLBINPPL1INPP5BINPP5A | |
| Ethylenediamine SCHEMBL29045380 | 0.81 | MAPT (0.62) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL108985 | 0.80 | MAPT (0.71) | MAPTPOLBINPPL1INPP5BINPP5A | |
| SCHEMBL28671333 | 0.80 | MAPT (0.61) | MAPTPOLBINPPL1INPP5BINPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | HDGF, CD40LG, PPIP5K2 | MAPT 4840/4885POLB 3199/4885INPPL1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.