SCHEMBL4334565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4336829	0.87	KDM4E (0.43)	MAPTMEN1KMT2AKDM4EHSD17B10
	SCHEMBL2866722	0.85	GSK3B (0.41)	JAK2JAK3DRD2
	SCHEMBL4341547	0.85	BRD4 (0.46)	MAPTMEN1KMT2AKDM4EHSD17B10
	SCHEMBL4341426	0.84	GAA (0.50)	LMNAMAPTMEN1KMT2AKDM4E
	SCHEMBL2862928	0.83	PIP5K1C (0.46)	MAPTMEN1KMT2AKDM4EHSD17B10
	SCHEMBL4348178	0.83	LMNA (0.45)	LMNAMAPTMEN1KMT2AMAPK1
	SCHEMBL4331838	0.83	HPGD (0.53)	MEN1KMT2AKDM4EHSD17B10ALDH1A1
	SCHEMBL4343252	0.83	HSD17B10 (0.49)	MAPTMEN1KMT2AKDM4EHSD17B10
	SCHEMBL4327612	0.83	JAK2 (0.40)	MAPTMEN1KMT2AKDM4EHSD17B10
	SCHEMBL4331216	0.83	JAK2 (0.39)	MAPTMEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.