Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322895 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HTTNPSR1 | |
| SCHEMBL4330972 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL4326314 | 0.86 | HTT (0.47) | KDM4EALDH1A1HSD17B10HTTNPSR1 | |
| SCHEMBL4332629 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HTTADORA2A | |
| SCHEMBL4318744 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HTTNPSR1 | |
| SCHEMBL4330467 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10HTTADORA2A | |
| SCHEMBL4332310 | 0.80 | ATR (0.47) | KDM4EALDH1A1HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL4335813 | 0.78 | PDE4A (0.52) | SMN1; SMN2ADORA2APOLBADORA1 | |
| SCHEMBL4333097 | 0.78 | ADORA2A (0.45) | SMN1; SMN2ADORA2ACNR2ADORA1SLC40A1 | |
| SCHEMBL4329117 | 0.77 | ROCK2 (0.44) | KDM4EALDH1A1HSD17B10HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | KDM4E 2430/4885ALDH1A1 2838/4885HSD17B10 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.