Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207545 | 0.93 | HSD17B3 (0.75) | HSD17B3NPC1RAB9AESR1ESR2 | |
| SCHEMBL9483582 | 0.85 | HSD17B3 (0.62) | HSD17B3HTR7 | |
| SCHEMBL420677 | 0.85 | HSD17B3 (1.00) | HSD17B3NPC1RAB9AESR1HTR7 | |
| SCHEMBL28294449 | 0.84 | HTR7 (0.74) | HSD17B3NPC1RAB9AHTR7SMN1; SMN2 | |
| SCHEMBL6602564 | 0.84 | CES1 (0.58) | HSD17B3NPC1RAB9AHTR7LMNA | |
| SCHEMBL13882426 | 0.83 | HSD17B3 (0.69) | HSD17B3NPC1RAB9AESR1HTR7 | |
| SCHEMBL12075203 | 0.83 | HSD17B3 (0.59) | HSD17B3NPC1RAB9AESR1HTR7 | |
| SCHEMBL11137804 | 0.81 | NPC1 (0.50) | HSD17B3NPC1RAB9AHTR7LMNA | |
| SCHEMBL585367 | 0.81 | HDAC1 (0.57) | NPC1RAB9ALMNAMAPK1ALDH1A1 | |
| SCHEMBL18286487 | 0.81 | MMP1 (0.64) | NPC1TSHRLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636670-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2636670-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2016-06-01 | — | — | EP | disclosed |
| CN-103342633-B | For the preparation of the method for benzofuran compounds | CAMBREX KARLSKOGA AB (SE) | 2016-05-04 | — | — | CN | disclosed |
| EP-2417099-B1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2417099-B1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2015-12-23 | — | — | EP | disclosed |
| CN-102459154-B | For the preparation of the novel method of azanol class and medicine | CAMBREX KARLSKOGA AB (SE) | 2015-12-02 | — | — | CN | disclosed |
| EP-2388256-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2388256-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| CN-102171200-B | For the preparation of the method for diones and medicine | CAMBREX KARLSKOGA AB (SE) | 2015-09-30 | — | — | CN | disclosed |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2014-07-24 | — | — | US | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| EP-2246341-A1 | Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans | Lonza Ltd. (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010116140-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-10-14 | — | — | WO | disclosed |
| EP-2200993-A2 | PROCESS FOR PREPARING BENZOFURANS | Cambrex Karlskoga AB (SE) | 2010-06-30 | — | — | EP | disclosed |
| WO-2010040261-A1 | PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS | LONZA LTD (CH) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010038029-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010038029-A1 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| WO-2009044143-A2 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CYP3A4, CYP1A2, CYP2D6 | HSD17B3 452/4885NPC1 1204/4885RAB9A 1617/4885 |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CYP2F1, CYP3A4, CYP4F3 | HSD17B3 453/4885NPC1 905/4885RAB9A 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.