Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ATF4 | P18848 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341174 | 0.92 | PPARG (0.38) | PLA2G4AMTNR1AMTNR1BMCL1PPARG | |
| SCHEMBL4329911 | 0.91 | PLA2G4A (0.44) | PLA2G4AMTNR1AMTNR1BMCL1PPARG | |
| SCHEMBL13819541 | 0.90 | PLA2G4A (0.36) | PLA2G4AMTNR1AMTNR1BMCL1NQO2 | |
| SCHEMBL4342749 | 0.89 | PLA2G4A (0.42) | PLA2G4AMTNR1AMTNR1BMCL1PPARG | |
| SCHEMBL4337058 | 0.88 | PLA2G4A (0.41) | PLA2G4AMTNR1AMTNR1BMCL1PPARG | |
| SCHEMBL4343659 | 0.88 | PLA2G4A (0.41) | PLA2G4APPARGPPARAADA | |
| SCHEMBL4339112 | 0.87 | MRGPRX4 (0.36) | PLA2G4AMTNR1AMTNR1BMCL1NQO2 | |
| SCHEMBL4331747 | 0.84 | PPARG (0.42) | PLA2G4AMTNR1AMTNR1BMCL1PPARG | |
| SCHEMBL4328073 | 0.83 | PLA2G4A (0.38) | PLA2G4AADA | |
| SCHEMBL4341738 | 0.82 | KMT2A (0.39) | MTNR1AMTNR1BPPARGPPARAADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522944-C | Carboxylic acid derivatives and salts thereof | EISAI CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| CN-1503774-A | Carboxylic acid derivatives and salts thereof | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | PLA2G4A 3556/4885ICMT 4219/4885MTNR1A 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.