Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 8/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | FSHR | P23945 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17467741 | 0.91 | LHCGR (0.82) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4322522 | 0.90 | LHCGR (0.81) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL6427025 | 0.88 | LHCGR (0.78) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4326072 | 0.87 | LHCGR (1.00) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL32156160 | 0.87 | LHCGR (1.00) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4331233 | 0.87 | LHCGR (0.77) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4430436 | 0.86 | LHCGR (0.77) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4419261 | 0.86 | LHCGR (0.77) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4325451 | 0.85 | LHCGR (0.75) | LHCGRTSHRBRAFPDE4APDE4B | |
| SCHEMBL4327416 | 0.85 | LHCGR (0.83) | LHCGRTSHRBRAFPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203716-A1 | Pyrimidine low molecular weight ligands for modulating hormone receptors | The Government of the United States of America as represented by the Secretary of the | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203716-A1 | Pyrimidine low molecular weight ligands for modulating hormone receptors | FSHR, TSHR, TRHR | LHCGR 5/4885TSHR 2/4885BRAF 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.