Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892413 | 0.84 | MIF (0.76) | MIFHTTCA1CA2TSHR | |
| SCHEMBL743565 | 0.81 | MIF (0.60) | MIFHTTNPC1CA1CA2 | |
| SCHEMBL4320204 | 0.81 | ALDH1A1 (0.66) | MIFHTTNPC1RAB9AMAPK10 | |
| SCHEMBL30390740 | 0.80 | MIF (0.58) | MIFHTTNPC1RAB9ACA1 | |
| SCHEMBL26102340 | 0.80 | MIF (0.58) | MIFHTTNPC1RAB9ACA1 | |
| SCHEMBL7399375 | 0.78 | MIF (1.00) | MIFHTTMAPK10ALDH1A1HPGD | |
| SCHEMBL14329797 | 0.78 | MIF (0.69) | MIFHTTNPC1RAB9ACA1 | |
| SCHEMBL4799736 | 0.78 | MIF (0.64) | MIFHTTCA1CA2MAPK10 | |
| SCHEMBL12556064 | 0.77 | MIF (1.00) | MIFHTTCA1CA2CYP1A2 | |
| SCHEMBL22861383 | 0.77 | MIF (1.00) | MIFHTTCA1CA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |