Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | APEX1 | P27695 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | GALK1 | P51570 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16080080 | 0.86 | KDM4E (0.83) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL431308 | 0.85 | KDM4E (0.82) | KDM4EMEN1MAPTRECQLKMT2A | |
| Theaflavin Monogallates SCHEMBL29349416 | 0.79 | BCL2 (0.78) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL15683002 | 0.78 | KDM4E (0.96) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL15489160 | 0.78 | KDM4E (0.84) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL13875103 | 0.78 | KDM4E (0.70) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL14399846 | 0.77 | KDM4E (0.67) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL17206814 | 0.77 | KDM4E (0.98) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL16440593 | 0.77 | KDM4E (0.98) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL16442190 | 0.77 | KDM4E (0.98) | KDM4EMEN1MAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065410-A1 | ANTI-OBESITY AGENT COMPRISING COMPOUND CONTAINING BENZOTROPOLONE RING | SUNTORY HOLDINGS LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065410-A1 | ANTI-OBESITY AGENT COMPRISING COMPOUND CONTAINING BENZOTROPOLONE RING | PNLIP, GAA, LIPC | KDM4E 1234/4885MEN1 4806/4885MAPT 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.