SCHEMBL4335831

SCHEMBL4335831

CC(OC(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700475 0.86 TSHR (0.31)
SCHEMBL4335833 0.84 THRB (0.33) THRB
SCHEMBL2400717 0.79 TSHR (0.38)
SCHEMBL1263586 0.78 TSHR (0.37)
SCHEMBL11904925 0.77 TSHR (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL12095052 0.75 RORC (0.34)
SCHEMBL701888 0.75 RORC (0.34)
SCHEMBL7543884 0.75 HCAR2 (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL28569591 0.75 THRB (0.34) THRBCA1CA2MMP1MMP2
SCHEMBL7543886 0.75 HCAR2 (0.39) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253044-A1 Nonaqueous Electrolyte and Lithium ion Secondary Battery Using Same MITSUI CHEMICALS, INC. (JP) 2009-10-08 US disclosed