Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327337 | 0.89 | PPARG (0.50) | LMNAPPARAPPARGPPARDALDH1A1 | |
| SCHEMBL4343603 | 0.89 | GAA (0.47) | LMNAMAPK1NLRP1PPARAERCC1 | |
| SCHEMBL13810608 | 0.89 | LMNA (0.44) | LMNAMAPK1NLRP1PPARAP2RX7 | |
| SCHEMBL4328023 | 0.84 | GAA (0.44) | LMNAPPARATDP1PPARGL3MBTL1 | |
| SCHEMBL4339331 | 0.82 | ATM (0.46) | LMNAPPARAPPARGL3MBTL1PPARD | |
| SCHEMBL4339328 | 0.82 | ATM (0.46) | LMNAPPARAPPARGL3MBTL1PPARD | |
| SCHEMBL4333276 | 0.79 | PPARG (0.48) | LMNAPPARAPPARGPPARDALDH1A1 | |
| SCHEMBL13810610 | 0.79 | PPARG (0.48) | LMNAPPARAPPARGPPARDALDH1A1 | |
| SCHEMBL4345817 | 0.79 | PPARG (0.50) | LMNAPPARAPPARGPPARDALDH1A1 | |
| SCHEMBL4328778 | 0.78 | GAA (0.47) | MAPK1PPARAPPARGL3MBTL1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | LMNA 3790/4885MAPK1 698/4885NLRP1 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.