Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 7/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336337 | 1.00 | CYP2D6 (0.33) | CYP2D6GAAMAPTTDP1MLYCD | |
| SCHEMBL19236789 | 0.84 | GAA (0.37) | GAAMAPT | |
| SCHEMBL19208043 | 0.83 | ALDH1A1 (0.31) | MAPTTDP1 | |
| SCHEMBL28803305 | 0.83 | ALDH1A1 (0.31) | MAPTTDP1 | |
| SCHEMBL5001765 | 0.78 | CA1 (0.45) | CYP2D6L3MBTL1CA1CA2CA7 | |
| SCHEMBL5001764 | 0.78 | CA1 (0.45) | CYP2D6L3MBTL1CA1CA2CA7 | |
| SCHEMBL16689247 | 0.75 | CYP2D6 (0.38) | CYP2D6MLYCDBTN3A1 | |
| SCHEMBL23247723 | 0.74 | CYP2D6 (0.36) | CYP2D6MLYCDBTN3A1 | |
| SCHEMBL26926905 | 0.74 | BTN3A1 (0.32) | CYP2D6BTN3A1 | |
| SCHEMBL1508734 | 0.73 | CYP2D6 (0.42) | CYP2D6GAAMAPTTDP1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612068-B2 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2009-11-03 | — | — | US | disclosed |
| US-20060235003-A1 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235003-A1 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | TYR, TPST2, COMT | CYP2D6 75/4885GAA 861/4885MAPT 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.