Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331689 | 0.87 | CREBBP (0.43) | ALDH1A1KMT2AMCL1POLBL3MBTL1 | |
| SCHEMBL4334672 | 0.87 | CREBBP (0.48) | ALDH1A1KMT2AMCL1MAPTCREBBP | |
| SCHEMBL6727386 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2AMCL1POLBL3MBTL1 | |
| SCHEMBL4333208 | 0.85 | CREBBP (0.42) | ALDH1A1KMT2AMCL1POLBL3MBTL1 | |
| SCHEMBL12874520 | 0.76 | KMT2A (0.66) | ALDH1A1KMT2AMCL1TBXAS1KDM4E | |
| SCHEMBL26851045 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KMT2AMCL1TBXAS1KDM4E | |
| SCHEMBL4340097 | 0.75 | PPARG (0.45) | ALDH1A1KDM4EMAPTCREBBP | |
| SCHEMBL4339994 | 0.74 | CYP4F2 (0.50) | ALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL27268451 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KMT2AMCL1TBXAS1KDM4E | |
| SCHEMBL22188706 | 0.73 | ALDH1A1 (0.65) | ALDH1A1KMT2AMCL1TBXAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |