Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331689 | 0.87 | CREBBP (0.43) | CREBBPMCL1CDC25AALDH1A1MAPT | |
| SCHEMBL4336487 | 0.87 | ALDH1A1 (0.52) | CREBBPMCL1ALDH1A1MAPTRECQL | |
| SCHEMBL4340097 | 0.86 | PPARG (0.45) | CREBBPALDH1A1MAPT | |
| SCHEMBL6727371 | 0.86 | CREBBP (0.45) | CREBBPMCL1CNR2CDC25AICMT | |
| SCHEMBL4333208 | 0.85 | CREBBP (0.42) | CREBBPMCL1CDC25AALDH1A1MAPT | |
| SCHEMBL4339994 | 0.77 | CYP4F2 (0.50) | ALDH1A1LMNAKMT2A | |
| SCHEMBL6727386 | 0.72 | ALDH1A1 (0.48) | MCL1CDC25AALDH1A1MAPTLMNA | |
| SCHEMBL29982103 | 0.72 | MAPT (0.64) | CREBBPMCL1CNR2CDC25AICMT | |
| SCHEMBL4332421 | 0.72 | SPR (0.47) | ALDH1A1MAPTALOX5LMNAKMT2A | |
| SCHEMBL6724709 | 0.72 | PPARA (0.46) | CREBBPMCL1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522944-C | Carboxylic acid derivatives and salts thereof | EISAI CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| CN-1503774-A | Carboxylic acid derivatives and salts thereof | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |