Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336772 | 1.00 | EPHX1 (0.42) | EPHX1NSD2ADAMTS4MMP13TNKS | |
| SCHEMBL4339550 | 0.83 | PPARG (0.46) | EPHX1KCNA5PPARGPPARASMN1; SMN2 | |
| SCHEMBL4336775 | 0.83 | EPHX1 (0.41) | EPHX1NSD2ADAMTS4MMP13TNKS | |
| SCHEMBL4329717 | 0.81 | CYSLTR1 (0.49) | — | |
| SCHEMBL4329708 | 0.81 | CYSLTR1 (0.49) | — | |
| SCHEMBL4329917 | 0.81 | DNMT1 (0.40) | ADAMTS4MMP13DNMT1DNMT3APPARG | |
| SCHEMBL4339545 | 0.80 | PIN1 (0.43) | TNKSTNKS2SMN1; SMN2 | |
| SCHEMBL4339543 | 0.80 | PIN1 (0.43) | TNKSTNKS2SMN1; SMN2 | |
| SCHEMBL4333374 | 0.80 | PPARA (0.46) | KCNA5PPARGPPARAPPARD | |
| SCHEMBL4329382 | 0.79 | MAPT (0.47) | CTSLCTSSKCNA5NAMPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |