Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336772 | 0.83 | EPHX1 (0.42) | EPHX1NSD2TNKSTNKS2DNMT1 | |
| SCHEMBL4336778 | 0.83 | EPHX1 (0.42) | EPHX1NSD2TNKSTNKS2DNMT1 | |
| SCHEMBL4329711 | 0.82 | CYSLTR1 (0.49) | — | |
| SCHEMBL4334154 | 0.80 | LMNA (0.44) | CASP1ALDH1A1MAPT | |
| SCHEMBL4339537 | 0.80 | HDAC1 (0.40) | EPHX1TNKSTNKS2KCNA5NAMPT | |
| SCHEMBL4342514 | 0.79 | ALDH1A1 (0.42) | CASP3ALDH1A1MAPT | |
| SCHEMBL4348232 | 0.79 | CASP1 (0.36) | EPHX1TNKSTNKS2CASP1CASP3 | |
| SCHEMBL4334667 | 0.78 | NPC1 (0.49) | CASP1ALDH1A1MAPT | |
| SCHEMBL4334187 | 0.78 | FFAR1 (0.49) | — | |
| SCHEMBL4337917 | 0.77 | NR3C2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |