Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9667106 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2F2F10KCNH2MEN1 | |
| SCHEMBL10548817 | 0.83 | KCNH2 (0.41) | SMN1; SMN2F2F10KCNH2PRSS1 | |
| SCHEMBL9577114 | 0.81 | KCNH2 (0.46) | SMN1; SMN2F2F10KCNH2PRSS1 | |
| SCHEMBL2521152 | 0.78 | LTA4H (0.58) | SMN1; SMN2F2F10MEN1KMT2A | |
| SCHEMBL9519763 | 0.77 | KCNH2 (0.44) | SMN1; SMN2F2F10KCNH2MEN1 | |
| SCHEMBL9714305 | 0.77 | KCNH2 (0.44) | SMN1; SMN2F2F10KCNH2MEN1 | |
| SCHEMBL1680925 | 0.77 | LOXL2 (0.47) | F2F10KCNH2PRSS1PRSS2 | |
| SCHEMBL17391197 | 0.77 | KDM1A (0.41) | MEN1KMT2AMAPTTDP1 | |
| SCHEMBL11175776 | 0.77 | KCNH2 (0.44) | SMN1; SMN2F2F10KCNH2MEN1 | |
| SCHEMBL9198043 | 0.77 | KCNH2 (0.44) | SMN1; SMN2F2F10KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237227-A1 | Insecticidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-16 | — | — | EP | claimed |
| EP-0108679-B1 | DERIVATIVES OF CYCLOPROPANE-CARBOXYLIC ACID CONTAINING AN ALKYLTHIOCARBONYL GROUP AND A HALOGEN ATOM, THEIR PREPARATION, THEIR USE AS PARASITICIDES FOR PLANTS, ANIMALS AND PREMISES, AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-02-19 | — | — | EP | claimed |
| EP-0145179-A1 | Halo((phenoxypyridyl)methyl)esters, process for their preparation and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-19 | — | — | EP | claimed |
| EP-0041021-B1 | CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AGAINST PARASITES IN PLANTS AND ANIMALS, THEIR COMPOSITIONS AND THEIR INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | claimed |
| EP-0027011-B1 | INSECTICIDAL SYNERGISTIC MIXTURES OF 0,0-DIETHYL 0-(3,5,6-TRICHLORO-2-PYRIDINYL) PHOSPHOROTHIOATE AND 3-(2,2-DICHLOROETHENYL)-2,2-DIMETHYL-CYCLOPROPANE CARBOXYLIC ACID: CYANO (6-PHENOXY-2-PYRIDINYL) METHYL ESTER AND METHOD OF KILLING AND CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | claimed |
| EP-0037851-A2 | Carboxylates, a process for their production, an insecticidal and/or acaricidal composition and the use of the compounds as insecticides and/or acaricides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-21 | — | — | EP | claimed |
| EP-2048953-B1 | INSECTICIDAL COMPOSITION | MCLAUGHLIN GORMLEY KING CO (US) | 2020-11-18 | — | — | EP | disclosed |
| US-20090324509-A1 | INSECTICIDAL COMPOSITION | LIVIE BIOPESTICIDES LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090263511-A1 | INSECTICIDAL COMPOSITION | LIVIE BIOPESTICIDES LIMITED (GB) | 2009-10-22 | — | — | US | disclosed |
| WO-2005087742-A1 | METABOLIC KINASE MODULATORS AND METHODS OF USE AS PESTICIDES | EXELIXIS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-4883806-A | ACARICIDES | ROUSSEL UCLAF (FR) | 1989-11-28 | — | — | US | disclosed |
| US-4833163-A | INSECTICIDES, NEMATOCIDES, MITICIDES | ROUSSEL UCLAF (FR) | 1989-05-23 | — | — | US | disclosed |
| EP-0237227-A1 | Insecticidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-16 | — | — | EP | disclosed |
| EP-0162538-A2 | Cyclopropane derivates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-27 | — | — | EP | disclosed |
| US-4542142-A | Insecticidal cyclopropane carboxylic acid derivatives with 3-unsaturated-side chain | ROUSSEL UCLAF (FR) | 1985-09-17 | — | — | US | disclosed |
| EP-0145179-A1 | Halo((phenoxypyridyl)methyl)esters, process for their preparation and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-19 | — | — | EP | disclosed |
| US-4491585-A | Combating pests with novel phenoxypyridylmethyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | disclosed |
| EP-0037851-A2 | Carboxylates, a process for their production, an insecticidal and/or acaricidal composition and the use of the compounds as insecticides and/or acaricides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-21 | — | — | EP | disclosed |
| EP-0026650-A3 | INSECTICIDAL SYNERGISTIC MIXTURES OF 0,0-DIETHYL 0-(3,5,6-TRICHLORO-2-PYRIDINYL)PHOSPHOROTHIOATE AND 4-CHLORO-ALPHA-(1-METHYLETHYL)BENZENE-ACETIC ACID:CYANO(6-PHENOXY-2-PYRIDINYL)METHYL ESTER AND METHOD OF KILLING AND CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1981-04-22 | — | — | EP | disclosed |
| EP-0026650-A2 | Insecticidal synergistic mixtures of 0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)phosphorothioate and 4-chloro-alpha-(1-methylethyl)benzene-acetic acid:cyano(6-phenoxy-2-pyridinyl)methyl ester and method of killing and controlling insects | THE DOW CHEMICAL COMPANY (US) | 1981-04-08 | — | — | EP | disclosed |