Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341877 | 1.00 | HDAC1 (0.55) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4340116 | 0.93 | HDAC1 (0.61) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4343415 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4320520 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4322299 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4326205 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL4333120 | 0.89 | PTGDR2 (0.50) | — | |
| SCHEMBL4335205 | 0.89 | PTGDR2 (0.50) | — | |
| SCHEMBL4331308 | 0.82 | PPARD (0.49) | — | |
| SCHEMBL4329549 | 0.82 | PPARD (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521563-B2 | Hydroxamic acid derivative and medicine containing the same as active ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2009-04-21 | — | — | US | claimed |
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-09-06 | — | — | US | claimed |
| EP-1787986-A1 | HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-05-23 | — | — | EP | claimed |
| US-7521563-B2 | Hydroxamic acid derivative and medicine containing the same as active ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1787986-A1 | HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | IL6, IL1A, TNF | HDAC1 27/4885HDAC2 69/4885HDAC7 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.