Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4333945 | 0.99 | HPGD (0.44) | HPGDKCNA5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4328756 | 0.82 | CA12 (0.43) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL1578391 | 0.80 | KCNA5 (0.49) | HPGDKCNA5 | |
| Hydrochloric Acid SCHEMBL1578094 | 0.79 | KCNA5 (0.49) | HPGDKCNA5 | |
| SCHEMBL4327258 | 0.78 | CA12 (0.50) | HPGDKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL4320987 | 0.74 | KCNA5 (0.39) | HPGDKCNA5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2209475 | 0.69 | KCNA5 (0.56) | HPGDKCNA5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17301589 | 0.68 | SMN1; SMN2 (0.69) | HPGDKCNA5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10534737 | 0.68 | AOX1 (0.47) | HPGDSMN1; SMN2NAAAHTTKDM4E | |
| SCHEMBL11087644 | 0.67 | NPC1 (0.63) | HPGDKCNA5SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |