Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327258 | 0.87 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4336831 | 0.82 | HPGD (0.44) | ALDH1A1MEN1KMT2AHTTRAB9A | |
| Hydrochloric Acid SCHEMBL4333945 | 0.81 | HPGD (0.44) | ALDH1A1MEN1KMT2AHTTRAB9A | |
| SCHEMBL1578291 | 0.80 | EGFR (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL313991 | 0.80 | BLM (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7312913 | 0.80 | BLM (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4333892 | 0.80 | NPC1 (0.49) | ALDH1A1MEN1KMT2AHTTRAB9A | |
| SCHEMBL1578073 | 0.78 | POLB (0.41) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL1995440 | 0.75 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8729705 | 0.74 | NPC1 (0.58) | RAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |