SCHEMBL4337123

SCHEMBL4337123

C=CNS(=O)(=O)c1ccc(N=Nc2ccc(O)c(C(=O)O)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 6/20 0.65
ALDH1A1 P00352 4/20 0.65
CYP2C9 P11712 2/20 0.65
PTGS1 P23219 2/20 0.65
PTGS2 P35354 2/20 0.65
HSD17B10 Q99714 2/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
SLC7A11 Q9UPY5 3/20 0.65
BLVRB P30043 2/20 0.65
TSHR P16473 2/20 0.65
HRH3 Q9Y5N1 2/20 0.65
HPGD P15428 2/20 0.65
ABCC3 O15438 1/20 0.65
ABCC4 O15439 1/20 0.65
USP2 O75604 1/20 0.65
SLCO2B1 O94956 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
LMNA P02545 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497248 0.90 PHLPP2 (0.65) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL4398148 0.90 PHLPP2 (0.65) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL4908604 0.83 PHLPP2 (0.70) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL4908605 0.83 PHLPP2 (0.70) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL11159188 0.82 ALDH1A1 (0.71) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL11159193 0.82 ALDH1A1 (0.71) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL3161638 0.80 PHLPP2 (0.65) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL3160549 0.80 PHLPP2 (0.65) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
Salazosulfamide SCHEMBL6432001 0.79 PTGS2 (1.00) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2
SCHEMBL5576043 0.79 PHLPP2 (0.78) PHLPP2ALDH1A1CYP2C9PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563560-B1 Solution and method for manufacturing an integrated circuit ADVANCED MICRO DEVICES, INC. (US) 2009-07-21 US claimed
US-7563560-B1 Solution and method for manufacturing an integrated circuit ADVANCED MICRO DEVICES, INC. (US) 2009-07-21 US disclosed