Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.65 |
| ▸ | BLVRB | P30043 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497248 | 1.00 | PHLPP2 (0.65) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL4337123 | 0.90 | PHLPP2 (0.65) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL4908604 | 0.83 | PHLPP2 (0.70) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL4908605 | 0.83 | PHLPP2 (0.70) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL11159188 | 0.82 | ALDH1A1 (0.71) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL11159193 | 0.82 | ALDH1A1 (0.71) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL3161638 | 0.80 | PHLPP2 (0.65) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL3160549 | 0.80 | PHLPP2 (0.65) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| Salazosulfamide SCHEMBL6432001 | 0.79 | PTGS2 (1.00) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 | |
| SCHEMBL5576043 | 0.79 | PHLPP2 (0.78) | PHLPP2ALDH1A1CYP2C9PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170188905-A1 | BIOINTERFACE LAYER FOR ANALYTE SENSORS | DEXCOM, INC. | 2017-07-06 | — | — | US | disclosed |
| US-9393217-B2 | Self assembled films for protein and drug delivery applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150086599-A1 | Self Assembled Films for Protein and Drug Delivery Applications | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-03-26 | — | — | US | disclosed |
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-10-15 | — | — | US | disclosed |
| US-7112361-B2 | Methods of making decomposable thin films of polyelectrolytes and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | NGLY1, VIP, PCBP1 | PHLPP2 466/4885ALDH1A1 4620/4885CYP2C9 4807/4885 |
| US-20170188905-A1 | BIOINTERFACE LAYER FOR ANALYTE SENSORS | PUF60, AGER, SLC2A8 | PHLPP2 1687/4885ALDH1A1 2692/4885CYP2C9 4751/4885 |
| US-20150086599-A1 | Self Assembled Films for Protein and Drug Delivery Applications | SERPINA6, ECPAS, BMP6 | PHLPP2 92/4885ALDH1A1 4309/4885CYP2C9 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.