Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926507 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL4335276 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTABCB1KDM4E | |
| SCHEMBL385218 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRHTTLMNASMN1; SMN2 | |
| SCHEMBL28020498 | 0.85 | ALDH1A1 (0.74) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL25063217 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL24074185 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL28020074 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL5835155 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL28020536 | 0.83 | TSHR (0.61) | ALDH1A1TSHRHTTABCB1ADRB2 | |
| SCHEMBL27842193 | 0.82 | ABCB1 (0.66) | ALDH1A1TSHRHTTABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247734-B1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-08-31 | — | — | EP | disclosed |
| US-10370491-B2 | Preparation of highly heat-resistant (co)polycarbonates by the transesterification method | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20170369642-A1 | Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3247734-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | Covestro Deutschland AG (DE) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016116480-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO DEUTSCHLAND AG (DE) | 2016-07-28 | — | — | WO | disclosed |
| US-20090117314-A1 | PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD | BAYER MATERIALSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |