SCHEMBL433743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29979812	1.00	MAPT (0.36)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL434599	0.92	MAPT (0.34)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL29979255	0.92	MAPT (0.34)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL674871	0.84	ALDH1A1 (0.35)	MAPTLMNAHPGDCYP3A4ALDH1A1
	SCHEMBL675367	0.82	MAPT (0.37)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL675590	0.82	MAPT (0.37)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL4595502	0.81	CYP1A2 (0.36)	MAPTLMNAKDM4EHPGDCYP1A2
	SCHEMBL677209	0.81	MAPT (0.40)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL6249025	0.80	MAPT (0.33)	MAPTLMNAKDM4EHPGDTP53
	SCHEMBL675825	0.79	AURKA (0.38)	MAPTLMNAKDM4EHPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.