SCHEMBL434599

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29979255	1.00	MAPT (0.34)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL29979812	0.92	MAPT (0.36)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL433743	0.92	MAPT (0.36)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL6249025	0.88	MAPT (0.33)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL675856	0.86	PTPN1 (0.35)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL4595972	0.84	LMNA (0.35)	MAPTLMNAHPGDKDM4EGAA
	SCHEMBL6247176	0.84	KMT2A (0.36)	MAPTLMNAHPGDCYP3A4KMT2A
	SCHEMBL675367	0.83	MAPT (0.37)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL675590	0.83	MAPT (0.37)	MAPTLMNAHPGDKDM4ETP53
	SCHEMBL4595502	0.82	CYP1A2 (0.36)	MAPTLMNAHPGDKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.