Phosphoric Acid

Phosphoric Acid

SCHEMBL433830

O=P(O)(O)O.Oc1c[nH]c2cc(Cl)c(Br)cc12

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA1A known ✓ P35348 1/20 0.33
CSNK2A1 P68400 3/20 0.47
AR P10275 1/20 0.36
PRKAB2 O43741 7/20 0.35
PRKAG1 P54619 7/20 0.35
PRKAA2 P54646 7/20 0.35
PRKAA1 Q13131 7/20 0.35
PRKAG3 Q9UGI9 7/20 0.35
PRKAG2 Q9UGJ0 7/20 0.35
PRKAB1 Q9Y478 7/20 0.35
CYP1A2 P05177 1/20 0.35
GSK3B P49841 1/20 0.35
GPR84 Q9NQS5 2/20 0.32
HAVCR2 Q8TDQ0 1/20 0.31
GUSB P08236 1/20 0.31
AXL P30530 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153945 0.92 CSNK2A1 (0.53) CSNK2A1ARPRKAB2PRKAG1PRKAA2
Sulfuric Acid SCHEMBL431766 0.87 CSNK2A1 (0.47) CSNK2A1ARPRKAB2PRKAG1PRKAA2
Acetic Acid SCHEMBL4228443 0.86 CSNK2A1 (0.46) CSNK2A1ARPRKAB2PRKAG1PRKAA2
Sulfuric Acid SCHEMBL14840231 0.86 CSNK2A1 (0.46) CSNK2A1ARPRKAB2PRKAG1PRKAA2
Choline SCHEMBL7041896 0.81 CSNK2A1 (0.38) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL27616205 0.81 CSNK2A1 (0.47) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1
Butyric Acid SCHEMBL433437 0.80 CYP1A2 (0.46) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL29285132 0.79 CSNK2A1 (0.46) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL307261 0.77 CSNK2A1 (0.43) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL29351558 0.77 CSNK2A1 (0.43) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11505816-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same KIKKOMAN CORPORATION (JP) 2022-11-22 US claimed
CN-108603215-B Culture medium for detecting staphylococcus aureus, staphylococcus aureus detection sheet having the same, and method for detecting staphylococcus aureus using the same 龟甲万株式会社 2022-10-14 CN claimed
US-10822632-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same DAI NIPPON PRINTING CO., LTD. (JP) 2020-11-03 US claimed
EP-3409784-B1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS DAINIPPON PRINTING CO LTD (JP) 2020-10-07 EP claimed
US-20200298233-A1 MICROFLUIDIC PAPER CHIP FOR DETECTING MICRO-ORGANISM, METHOD FOR PREPARING THE SAME AND METHOD FOR DETECTING MICRO-ORGANISM USING THE SAME BIOMAX CO., LTD. (KR) 2020-09-24 US claimed
US-20190024136-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2019-01-24 US claimed
EP-3409784-A1 MEDIUM FOR DETECTINGSTAPHYLOCOCCUS AUREUS Dai Nippon Printing Co., Ltd. (JP) 2018-12-05 EP claimed
EP-1543147-B2 METHOD OF DETECTING METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2011-03-16 EP claimed
EP-1543147-B1 METHOD OF DETECTING METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2006-12-20 EP claimed
EP-1165831-B1 CHROMOGENIC MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2006-05-31 EP claimed
EP-1543147-A1 METHOD OF DETECTING METICILLIN-RESISTANT MICRO-ORGANISMS Rambach, Alain (FR) 2005-06-22 EP claimed
US-6902586-B2 Phosphate dye precursors and use thereof for dyeing keratin fibers L'OREAL (FR) 2005-06-07 US claimed
US-20040235012-A1 Method of detecting antibiotic resistance in microorganisms BECTON, DICKINSON AND COMPANY 2004-11-25 US claimed
EP-1273283-B1 Phosphated dye precursors and their application for dyeing keratinous fibres OREAL (FR) 2004-10-06 EP claimed
WO-2004063391-A1 METHOD OF DETECTING ANTIBIOTIC RESISTANCE IN MICROORGANISMS BECTON, DICKINSON AND COMPANY (US) 2004-07-29 WO claimed
WO-2004027086-A1 METHOD OF DETECTING METICILLIN-RESISTANT MICRO-ORGANISMS RAMBACH ALAIN (FR) 2004-04-01 WO claimed
US-6548268-B1 A medium for isolating Staphylococcus aureus, comprises in a culture medium of Staphylococcus aureus atleast one of chromogenic agents:5-bromo-6-chloro-3-indoxylphosphate and 5-bromo-6-chloro-glucoside; and also contains deferoxamine RAMBACH ALAIN (FR) 2003-04-15 US claimed
US-20030037387-A1 Phosphate dye precursors and use thereof for dyeing keratin fibres L'OREAL (FR) 2003-02-27 US claimed
EP-1165831-A1 CHROMOGENIC MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS Rambach, Alain (FR) 2002-01-02 EP claimed
WO-2000053799-A1 CHROMOGENIC MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2000-09-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030037387-A1 Phosphate dye precursors and use thereof for dyeing keratin fibres KRT18, ALPG, ALPP ADRA1A 4690/4885CSNK2A1 1101/4885AR 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.