Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.37 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578105 | 0.96 | CNR2 (0.50) | CNR2HTR4CYP3A4EGLN2HPGD | |
| Trifluoroacetic Acid SCHEMBL4320267 | 0.91 | CNR2 (0.57) | CNR2HTR4CYP3A4EGLN2HPGD | |
| SCHEMBL13578093 | 0.87 | CNR2 (0.61) | CNR2HTR4CYP3A4EGLN2HPGD | |
| Trifluoroacetic Acid SCHEMBL4326435 | 0.84 | ALDH1A1 (0.50) | CNR2HPGDSMN1; SMN2KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4321817 | 0.84 | KDM4E (0.47) | CNR2HPGDSMN1; SMN2KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4327011 | 0.81 | TP53 (0.44) | CNR2HPGDPOLBALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4341463 | 0.81 | SMN1; SMN2 (0.40) | CNR2HPGDPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL4329757 | 0.80 | CNR2 (0.47) | CNR2HTR4L3MBTL1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4331110 | 0.80 | CNR2 (0.54) | CNR2HTR4CYP3A4HPGDPOLB | |
| Trifluoroacetic Acid SCHEMBL4326117 | 0.80 | TP53 (0.49) | CNR2SMN1; SMN2L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | CNR2 1/4885HTR4 254/4885CYP3A4 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.