Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459204 | 0.74 | NPSR1 (0.50) | LMNANPSR1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL7557322 | 0.74 | PDK2 (0.39) | LMNANPSR1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL15700144 | 0.72 | HTT (0.49) | LMNANPSR1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL30638044 | 0.67 | HTR2A (0.35) | TSHRMAOB | |
| SCHEMBL11154101 | 0.67 | GAA (0.39) | LMNAHTTL3MBTL1ALDH1A1POLB | |
| SCHEMBL11703613 | 0.66 | ALDH1A1 (0.41) | LMNANPSR1HTTL3MBTL1ALDH1A1 | |
| SCHEMBL11702895 | 0.66 | ALDH1A1 (0.38) | LMNANPSR1HTTALDH1A1POLB | |
| SCHEMBL11766239 | 0.66 | ALDH1A1 (0.35) | LMNANPSR1HTTALDH1A1POLB | |
| SCHEMBL11767673 | 0.66 | ALDH1A1 (0.35) | LMNANPSR1HTTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL11708273 | 0.65 | LMNA (0.37) | LMNAHTTALDH1A1POLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |