Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066905 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL1747928 | 0.79 | LMNA (0.66) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL969167 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL28787382 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL3790319 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL17987894 | 0.76 | PDPK1 (0.61) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL14127131 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL2749466 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAPDE10AMAPTTDP1 | |
| SCHEMBL2634141 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1LMNAMAPTTDP1GAA | |
| Nitrogen SCHEMBL27703821 | 0.76 | LMNA (0.61) | ALDH1A1LMNAPDE10AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149979-B | 8- (benzothiazole amide) substituted coumarin compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| WO-2022183961-A1 | 8-(BENZOTHIAZOLE AMIDE) SUBSTITUTED COUMARIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2022-09-09 | — | — | WO | claimed |
| CN-113149979-A | 8- (benzothiazole amide) substituted coumarin compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-113149979-B | 8- (benzothiazole amide) substituted coumarin compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022183961-A1 | 8-(BENZOTHIAZOLE AMIDE) SUBSTITUTED COUMARIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2022-09-09 | — | — | WO | disclosed |
| CN-113149979-A | 8- (benzothiazole amide) substituted coumarin compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | MCHR1, MCHR2, MC1R | ALDH1A1 1529/4885LMNA 3624/4885PDE10A 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.