Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332465 | 0.87 | ACACB (0.39) | ACACBL3MBTL1LMNAMMP8MAPK1 | |
| SCHEMBL4339684 | 0.86 | ACACB (0.40) | ACACBL3MBTL1LMNAMMP8MAPK1 | |
| SCHEMBL4336550 | 0.86 | PPARG (0.43) | FFAR1PPARGPPARA | |
| SCHEMBL4333099 | 0.84 | ACACB (0.46) | ACACBFFAR1PPARGPPARA | |
| SCHEMBL13810013 | 0.83 | GABRA1 (0.39) | ACACBL3MBTL1LMNAMAPK1TSHR | |
| SCHEMBL4341960 | 0.83 | ACACB (0.39) | ACACBL3MBTL1LMNAMMP8MAPK1 | |
| SCHEMBL4332258 | 0.82 | GRIA2 (0.42) | L3MBTL1LMNAMMP8MAPK1TSHR | |
| SCHEMBL4329899 | 0.82 | MMP8 (0.39) | L3MBTL1LMNAMMP8MAPK1TSHR | |
| SCHEMBL4332255 | 0.82 | GRIA2 (0.42) | L3MBTL1LMNAMMP8MAPK1TSHR | |
| SCHEMBL4339926 | 0.81 | MAPK1 (0.46) | L3MBTL1MAPK1TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522944-C | Carboxylic acid derivatives and salts thereof | EISAI CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |