SCHEMBL4339198

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4334940	0.86	MAP4K4 (0.48)	MAPK1JAK2JAK3MAP2K4NTRK1
	SCHEMBL4336457	0.85	MAPK1 (0.50)	MAPK1KDM4EALDH1A1HPGDJAK2
	SCHEMBL4340999	0.85	WNT1 (0.51)	MAPK1ALDH1A1MAPK8DYRK1AWNT1
	SCHEMBL4340944	0.85	DYRK1A (0.38)	MAPK1JAK2JAK3MAP2K4NTRK1
	SCHEMBL2872493	0.83	MAPK1 (0.57)	MAPK1NTRK1MAP3K5TTKMAPK8
	SCHEMBL4331947	0.80	NAMPT (0.45)	MAPK1JAK2JAK3LMNACDK4
	SCHEMBL4346817	0.80	TAAR1 (0.49)	MAPK1KDM4ELMNATTKCDK4
	SCHEMBL27536113	0.80	MAP2K4 (0.47)	JAK2JAK3MAP2K4NTRK1TTK
	SCHEMBL2864882	0.79	TP53 (0.53)	KDM4EALDH1A1HPGD
	SCHEMBL2866826	0.78	DYRK1A (0.52)	HPGDMAP2K4MAP3K5MAPK8DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.