Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341219 | 0.89 | PPARA (0.53) | PPARAPPARGPPARDHPGDNLRP1 | |
| SCHEMBL13819776 | 0.88 | MRGPRX4 (0.59) | PPARAPPARGHPGDMAPTL3MBTL1 | |
| SCHEMBL13819716 | 0.88 | MRGPRX4 (0.59) | PPARAPPARGHPGDMAPTL3MBTL1 | |
| SCHEMBL4336847 | 0.88 | PPARA (0.54) | PPARAPPARGPPARDHPGDNLRP1 | |
| SCHEMBL4336482 | 0.84 | PPARA (0.53) | PPARAPPARGPPARDHPGDMAPT | |
| SCHEMBL6651371 | 0.84 | PPARA (0.53) | PPARAPPARGPPARDHPGDMAPT | |
| SCHEMBL4336480 | 0.84 | PPARA (0.53) | PPARAPPARGPPARDHPGDMAPT | |
| SCHEMBL4341964 | 0.82 | MMP1 (0.50) | PPARAPPARGPPARDHPGDNLRP1 | |
| SCHEMBL4327910 | 0.81 | PPARA (0.51) | PPARAPPARGPPARDLMNAMEN1 | |
| SCHEMBL4327650 | 0.81 | PPARA (0.51) | PPARAPPARGPPARDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |