Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017512 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| Benzyl Benzoate SCHEMBL29079453 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL29079458 | 0.92 | ALDH1A1 (0.86) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL312287 | 0.86 | KMT2A (0.92) | ALDH1A1MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL3201572 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL8477951 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL29079463 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL6427557 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| Benzyl Benzoate SCHEMBL27589165 | 0.83 | TDP1 (0.92) | ALDH1A1MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL9837067 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148658-A | BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-10 | — | — | US | claimed |
| EP-3798214-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2021-03-31 | — | — | EP | disclosed |
| US-20180179203-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC. | 2018-06-28 | — | — | US | disclosed |
| US-20090092801-A1 | NONAQUEOUS INKJET INK, INK COMPOSITION FOR INKJET RECORDING, AND SUBSTRATE FOR COLOR FILTER | TOYO INK MANUFACTURING CO., LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| US-4148658-A | BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179203-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | RET, ROR1, BRAF | ALDH1A1 2706/4885MAPT 2183/4885HPGD 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.