Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488049 | 0.87 | SMN1; SMN2 (0.63) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL20458927 | 0.85 | KMT2A (0.63) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL312287 | 0.85 | KMT2A (0.92) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL13469241 | 0.83 | KMT2A (0.76) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL4339340 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL8961446 | 0.82 | KMT2A (0.79) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL3083135 | 0.82 | KMT2A (0.79) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| SCHEMBL7188228 | 0.81 | MAPT (0.58) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| Benzyl Benzoate SCHEMBL27589165 | 0.81 | TDP1 (0.92) | ALDH1A1MAPTHPGDKMT2ATDP1 | |
| Benzyl Benzoate SCHEMBL3038 | 0.81 | KMT2A (1.00) | ALDH1A1MAPTHPGDKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454773-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | Bundgaard, Hans (DK) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |