Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4339853

CCCc1ccc(C(F)(F)F)cc1CCC.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.42
PPARA Q07869 4/20 0.42
PPARD Q03181 3/20 0.42
HRH4 Q9H3N8 1/20 0.42
IDO1 P14902 2/20 0.40
DAO P14920 2/20 0.39
PDE2A O00408 1/20 0.39
CTSS P25774 2/20 0.38
CTSK P43235 2/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KIF11 P52732 1/20 0.36
HTR2A P28223 2/20 0.36
SLC6A4 P31645 2/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25977970 0.98 PPARG (0.43) PPARGPPARAPPARDHRH4IDO1
SCHEMBL12809047 0.90 PPARG (0.44) PPARGPPARAPPARDHRH4IDO1
SCHEMBL16956734 0.87 VDR (0.44) PPARGPPARAPPARDHRH4IDO1
SCHEMBL16950937 0.84 DAO (0.53) PPARGPPARAPPARDHRH4IDO1
SCHEMBL11068250 0.83 RXRA (0.51) PPARGPPARAPPARD
SCHEMBL2600180 0.82 IDO1 (0.54) PPARGPPARAPPARDHRH4IDO1
SCHEMBL13064211 0.82 IDO1 (0.54) PPARGPPARAPPARDHRH4IDO1
SCHEMBL13349970 0.82 DAO (0.51) PPARGPPARAPPARDHRH4IDO1
SCHEMBL12849193 0.82 PPARG (0.44) PPARGPPARAPPARDHRH4IDO1
SCHEMBL12203719 0.82 HRH4 (0.44) PPARGPPARAPPARDHRH4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1998616-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS Isagro Ricerca S.r.l. (IT) 2008-12-10 EP claimed
WO-2007101587-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 2007-09-13 WO claimed
EP-0792102-B1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS COMPRISING 4-BENZOYLISOXAZOLES AND 2,6-DINITROANILINE COMPOUNDS AVENTIS AGRICULTURE LTD (GB) 2001-01-24 EP claimed
EP-2094093-A2 HERBICIDAL COMPOSITIONS ISAGRO S.p.A. (IT) 2009-09-02 EP disclosed
EP-1998616-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS Isagro Ricerca S.r.l. (IT) 2008-12-10 EP disclosed
WO-2008071377-A2 HERBICIDAL COMPOSITIONS ISAGRO S.P.A. (IT) 2008-06-19 WO disclosed
WO-2007101587-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 2007-09-13 WO disclosed
EP-0792102-B1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS COMPRISING 4-BENZOYLISOXAZOLES AND 2,6-DINITROANILINE COMPOUNDS AVENTIS AGRICULTURE LTD (GB) 2001-01-24 EP disclosed
EP-0869715-B1 HERBICIDAL COMPOSITIONS RHONE POULENC AGRICULTURE (GB) 2000-04-26 EP disclosed