Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561304 | 0.88 | HTT (0.66) | HTTLMNASMN1; SMN2FOLH1ALDH1A1 | |
| SCHEMBL11376465 | 0.85 | HTT (0.70) | HTTLMNASMN1; SMN2FOLH1ALDH1A1 | |
| SCHEMBL13613756 | 0.84 | HTT (0.48) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| SCHEMBL11783251 | 0.83 | HTT (0.66) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| SCHEMBL126974 | 0.83 | HTT (0.66) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| SCHEMBL6741072 | 0.83 | LMNA (0.65) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| SCHEMBL10668714 | 0.83 | HTT (0.76) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL7285795 | 0.82 | HTT (0.57) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| Hydrochloric Acid SCHEMBL8688569 | 0.82 | HTT (0.64) | HTTLMNASMN1; SMN2ALDH1A1CTSL | |
| SCHEMBL16219550 | 0.81 | HTT (0.73) | HTTLMNASMN1; SMN2FOLH1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | MIMETICA PTY LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | IAPP, GLP1R, VIP | HTT 705/4885LMNA 1639/4885SMN1; SMN2 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.