Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172945 | 0.91 | LMNA (0.59) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL13644307 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL5217165 | 0.90 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL126974 | 0.89 | HTT (0.66) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL11783251 | 0.89 | HTT (0.66) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL7285795 | 0.89 | HTT (0.57) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL15561304 | 0.89 | HTT (0.66) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL7907133 | 0.88 | SYK (0.62) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| Hydrochloric Acid SCHEMBL8688569 | 0.87 | HTT (0.64) | LMNASMN1; SMN2HTTALDH1A1CTSL | |
| SCHEMBL10081124 | 0.87 | LMNA (0.63) | LMNASMN1; SMN2HTTALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135234-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2021-10-05 | — | — | US | disclosed |
| CN-108026133-B | Novel aminoglycoside antibiotics effective against multidrug resistant bacteria | 公益财团法人微生物化学研究会 | 2021-05-07 | — | — | CN | disclosed |
| US-20200155582-A1 | EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10617704-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-04-14 | — | — | US | disclosed |
| US-10576094-B2 | — | — | 2020-03-03 | — | — | US | disclosed |
| EP-3498723-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | Microbial Chemistry Research Foundation (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-20180214470-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-08-02 | — | — | US | disclosed |
| EP-3330275-A1 | NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA | Microbial Chemistry Research Foundation (JP) | 2018-06-06 | — | — | EP | disclosed |
| US-20040127477-A1 | Heterocyclic glycyl beta-alanine derivatives | G. D. SEARLE & CO. (US) | 2004-07-01 | — | — | US | disclosed |
| US-6689754-B1 | PIPERIDINE OR PYRIDINE DERIVATIVES; ALPHA V BETA 3 INTEGRIN ANTAGONISTS | G. D. SEARLE & CO. | 2004-02-10 | — | — | US | disclosed |
| EP-1070060-A1 | HETEROCYCLIC GLYCYL BETA-ALANINE DERIVATIVES AS VITRONECTIN ANTAGONISTS | G.D. Searle & Co. (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052896-A1 | HETEROCYCLIC GLYCYL BETA-ALANINE DERIVATIVES AS VITRONECTIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127477-A1 | Heterocyclic glycyl beta-alanine derivatives | ITGB3, ITGAL, ITGB1 | LMNA 972/4885SMN1; SMN2 811/4885HTT 4453/4885 |
| US-20180214470-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | ABCC1, SLC11A2, RPN2 | LMNA 2396/4885SMN1; SMN2 3376/4885HTT 3698/4885 |
| US-20200155582-A1 | EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | ABCC1, ABCB11, SLC11A2 | LMNA 2398/4885SMN1; SMN2 3037/4885HTT 3355/4885 |
| US-10617704-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | ABCC1, ABCB11, SLC11A2 | LMNA 2398/4885SMN1; SMN2 3037/4885HTT 3355/4885 |
| US-10576094-B2 | — | ALPI, REN, GMDS | LMNA 2645/4885SMN1; SMN2 2487/4885HTT 3770/4885 |
| US-11135234-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | ABCC1, ABCB11, SLC11A2 | LMNA 2398/4885SMN1; SMN2 3037/4885HTT 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.