Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654618 | 0.88 | KDM4E (0.39) | PPARGNR1I2AGTR2MEN1BLM | |
| SCHEMBL6654616 | 0.88 | KDM4E (0.39) | PPARGNR1I2AGTR2MEN1BLM | |
| SCHEMBL4328026 | 0.84 | CYP2D6 (0.47) | PPARGPPARACYP2D6CYP2C19PPARD | |
| SCHEMBL4347157 | 0.78 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL13810553 | 0.74 | PPARG (0.45) | PPARGMEN1KMT2APPARACYP2D6 | |
| SCHEMBL4474935 | 0.74 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL4338102 | 0.73 | NPC1 (0.48) | CYP2D6CYP2C19ALOX15KDM4E | |
| SCHEMBL4336608 | 0.73 | PPARG (0.42) | PPARGMEN1KMT2APPARAPPARD | |
| SCHEMBL4336526 | 0.73 | PPARG (0.45) | PPARGMEN1KMT2APPARACYP2C19 | |
| SCHEMBL4339997 | 0.73 | FFAR1 (0.42) | PPARGKMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |